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Alessio Nocentini Selected Research

Squamous Cell Carcinoma (Epidermoid Carcinoma)

10/2021Investigation of 3-sulfamoyl coumarins against cancer-related IX and XII isoforms of human carbonic anhydrase as well as cancer cells leads to the discovery of 2-oxo-2H-benzo[h]chromene-3-sulfonamide - A new caspase-activating proapoptotic agent.

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Alessio Nocentini Research Topics

Disease

90Neoplasms (Cancer)
02/2024 - 11/2015
18Glaucoma
01/2024 - 12/2016
11Hypoxia (Hypoxemia)
11/2023 - 10/2018
8Breast Neoplasms (Breast Cancer)
11/2023 - 10/2017
6Epilepsy (Aura)
12/2023 - 07/2017
5Neuralgia (Stump Neuralgia)
01/2023 - 01/2017
5Dandruff
01/2018 - 01/2016
4Colorectal Neoplasms (Colorectal Cancer)
11/2023 - 10/2017
4Arthritis (Polyarthritis)
10/2022 - 01/2018
3Neoplasm Metastasis (Metastasis)
10/2023 - 01/2023
3Chagas Disease (American Trypanosomiasis)
10/2022 - 04/2019
2Alzheimer Disease (Alzheimer's Disease)
03/2024 - 09/2019
2COVID-19
01/2024 - 04/2021
2Pathologic Processes
12/2023 - 01/2023
2Infections
11/2023 - 04/2021
2Carcinogenesis
10/2023 - 01/2023
2Dehydration (Water Stress)
05/2023 - 12/2019
2Pancreatic Neoplasms (Pancreatic Cancer)
12/2022 - 11/2017
2Acidosis
12/2022 - 05/2020
2Malaria
12/2022 - 12/2020
2Pain (Aches)
10/2022 - 12/2020
2Rheumatoid Arthritis
12/2020 - 01/2019
2Retinitis Pigmentosa (Pigmentary Retinopathy)
12/2019 - 01/2018
2Leishmaniasis
12/2019 - 04/2019
1Amyloid Plaque
03/2024
1Mitochondrial Diseases (Mitochondrial Disease)
03/2024
1Tuberculosis (Tuberculoses)
02/2024
1Nervous System Diseases (Neurological Disorders)
11/2023
1Triple Negative Breast Neoplasms
11/2023
1Ascites
01/2023
1CDKL5 deficiency disorder
01/2023
1Glioblastoma (Glioblastoma Multiforme)
12/2022

Drug/Important Bio-Agent (IBA)

75Protein Isoforms (Isoforms)IBA
01/2024 - 11/2015
69Carbonic Anhydrases (Carbonic Anhydrase)IBA
03/2024 - 11/2015
31SulfonamidesIBA
01/2024 - 11/2015
15BenzenesulfonamidesIBA
11/2023 - 05/2018
15Carbonic Anhydrase InhibitorsIBA
01/2023 - 10/2017
14EnzymesIBA
10/2023 - 01/2016
11Carbonic Anhydrase IXIBA
10/2023 - 12/2016
11CoumarinsIBA
12/2022 - 11/2015
9SLC-0111IBA
10/2023 - 12/2018
8IsoenzymesIBA
10/2023 - 12/2017
5coumarinIBA
02/2024 - 03/2020
5Acetazolamide (Diamox)FDA LinkGeneric
12/2022 - 01/2017
4AcidsIBA
12/2023 - 05/2020
4ProdrugsIBA
06/2022 - 12/2018
4ZincIBA
01/2020 - 10/2018
3Oxygen (Dioxygen)IBA
11/2023 - 01/2022
3Carboxylic AcidsIBA
01/2022 - 05/2020
2Reactive Oxygen Species (Oxygen Radicals)IBA
03/2024 - 04/2019
2SaltsIBA
02/2024 - 04/2019
2Antiviral Agents (Antivirals)IBA
01/2024 - 04/2021
2Carbonic Anhydrase IIIBA
01/2024 - 11/2019
2pyridazineIBA
01/2024 - 04/2019
2Doxorubicin (Adriamycin)FDA LinkGeneric
11/2023 - 10/2019
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2023 - 10/2023
2OxindolesIBA
11/2023 - 12/2018
2Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
11/2023 - 10/2023
2Proteins (Proteins, Gene)FDA Link
12/2022 - 10/2018
2Sulfonic AcidsIBA
12/2021 - 01/2021
2CaspasesIBA
12/2021 - 10/2021
2BenzopyransIBA
12/2021 - 10/2021
2OximesIBA
12/2021 - 10/2018
2benzofuranIBA
04/2021 - 05/2020
2dorzolamide (Trusopt)FDA LinkGeneric
01/2020 - 01/2018
2Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2020 - 11/2017
2Adrenergic Agents (Adrenergic Drugs)IBA
10/2019 - 01/2018
2Celecoxib (Celebrex)FDA Link
01/2018 - 01/2017
2CosmeticsIBA
01/2017 - 01/2016
1Amyloid (Amyloid Fibrils)IBA
03/2024
1MethazolamideFDA LinkGeneric
03/2024
1Peptides (Polypeptides)IBA
03/2024
1Cholinergic Agents (Cholinergics)IBA
03/2024
1Monoamine Oxidase (MAO)IBA
03/2024
1Isoniazid (Ftivazide)FDA LinkGeneric
02/2024
1Rifampin (Rifampicin)FDA LinkGeneric
02/2024
1triphenylphosphoniumIBA
02/2024
1CationsIBA
02/2024
1Guanidine (Guanidine Nitrate)FDA Link
02/2024
1Protease Inhibitors (Protease Inhibitor)IBA
01/2024
1SeleniumIBA
01/2024
1SARS-CoV-2 3C-like proteinaseIBA
01/2024
1Amino AlcoholsIBA
12/2023
1QuinazolinesIBA
12/2023
1BoronIBA
11/2023
1CateninsIBA
11/2023
1Biotin (Vitamin H)FDA Link
10/2023
1FITC-annexin A5IBA
10/2023
1IsothiocyanatesIBA
05/2023
1ThioureaIBA
05/2023
1Liposomes (Liposome)IBA
01/2023
1Antineoplastic Agents (Antineoplastics)IBA
01/2023
1Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2023
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
01/2023
1ChalconesIBA
12/2022
1benzothiazoleIBA
12/2022
1boric acid (boron oxide hydroxide)IBA
12/2022
1carbonic anhydrase XIIIBA
11/2022

Therapy/Procedure

13Therapeutics
02/2024 - 01/2017
2Radiotherapy
12/2022 - 05/2020